BB 656 - Introduction to Mechanobiology

Course content
  • Introduction to Mechanobiology
  • Alterations of Tissue/Cell
  • Properties in Diseases Extracellular Matrix (ECM) Composition
  • Basics of Stress and Strain
  • Rheological Characterization of Biopolymers
  • Physical Properties of Collagen Gels
  • Mechanosensitivity of Fibronectin
  • Composition of Focal Adhesions
  • Force Sensitivity of Focal adhesions
  • Effect of ECM properties on Cell Adhesion, Cell Spreading and Cell Migration
  • Since this course will be research-oriented, there is no official textbook other than original research papers and reviews identified by the instructor.
  • Students will be responsible for downloading and printing PDFs.
  • B. Alberts, D. Bray, J. Levis, M. Raff, K. Roberts & J. D. Watson: Molecular Biology of the Cell; 5th Ed, Garland Science
  • Fung, Y. C.: Biomechanics: Mechanical Properties of Living Tissues. 2nd Ed., Springer.
  • R. Kamm and M. K. Mofrad. Cytoskeletal Mechanics: Models and Measurements. Cambridge University Press.
Pre-requisite : N/A
Total credits : 6 credits - Lecture
Type : Core Course
Duration : Full Semester
Name(s) of other Academic units to whom the course may be relevant : N/A