CL 622 - Introduction to Computational Biology

Course description

Flood of data on genomics, transcriptomics, proteomics, phenomics, and xxx-omics has led to the emergence of a new interdisciplinary field where organization, analysis, and processing of this data has to be done efficiently. The biological databases are of many different kinds and more and more are emerging with the advent of the technology in the respective field. Although the different databases are related to each other, the link is not always clear. The challenge lies in understanding the link between these databases to glean new biological information. Another avenue is to apply systems science approaches to understand biology better. The course introduces students to biological databases, inter-and intra-database relationships, various algorithms, verbal models, quantitative models, etc. The course would cater to both biologists as well as non-biologists.

  • Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. A.D. Baxevanis and B.F.F .Ouellette. Wiley- Interscience (1998).
  • Introduction to Computational Biology: Maps, Sequences, Genomes. M.S.Waterman. Chapman & Hall (1995)
  • Biological Sequence Analysis: Probabilistic Models of proteins and Nucleic Acids, R. Durbin, S. Eddy, Akrogh, G. Mitchison, Cambridge University Press (1990).
  • Bioinformatics Basics: Applications in Biological Science and Medicine, H.H.Rashidi and L.K.Buchler, CRC Press (2001)
Total credits : 6 credits - Lecture and practical
Type : Department elective
Duration : Full Semester